Based on extensive expertise in dermatology and skin biology, PKDERM, a French biotech, offers a wide range of innovative in vitro tests and models to assess the efficacy and safety of new products. Activities in research and development, advice and training are in the fields of cosmetics, dermatology, pharmacy, chemicals, agro/petrochemicals, and medical devices.
Different biological models are used at PKDERM :
• Skin models (2D culture of keratinocytes, fibroblasts, melanocytes, etc.), 3D skin equivalent models, and human skin explants)
• Liver models (hepatocytes in 2D and 3D culture)
• 2D and 3D respiratory models (Calu-3, EpiAirway, PCLS…)
With more than 20 years of experience in pharmaceutical industry, PKDERM offers a wide range of innovative in vitro tests :
• Example of in vitro toxicology tests: dermal absorption, skin and eye irritation, sensitization, cytotoxicity, phototoxicity, endocrine properties, PK & metabolism, drug transporters and DDI.
Hanan OSMAN-PONCHET, PhD, Biochimie, Executive MBA